How to understand Renal Physiology

Renal Physiology is complex. But if you go step by step it is not so hard to understand…. Look at these videos to clarify your ideas

Renal Clearance

Here I tell you what renal clearance means and how it is calculated. In particular, what does creatinine clearance mean?

creatinine – virtual volume – FGR

Bicarbonate Reabsorption

Why is bicarbonate important

What is the role of kidney

How does nephrons reabsorb bicarbonate

Animation

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What is the Importance of Homeostasis and the Internal Environment

The first thing to focus on to understand physiology is homeostasis. Also, it is crucial to learn how the internal environment is regulated. We will try to get closer to these concepts. Let’s go for it!

 

How to estimate plasma volume

In this video, I describe the compartments of the body and how to estimate the volume of each compartment. Extracellular, Intracellular, Intravascular, Plasma. I also tell you how to estimate plasma volume and blood volume from weight and hematocrit.

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The best way to integrate Gastric Motility is to see it live!

I know that understanding gastric motility is very difficult. Then, some years ago I found that Prof. Dr. Hansjörg Ehrlein (University of Hohenheim, Germany) had made an actual live video recording an incredible videofluoroscopy of gastrointestinal motility. He also made some animations explaining how is the mechanism. Luckily they are on YouTube so below I will direct you to some videos. You can also find his explanations

Gastric Motor Function

Antral Pump
Antral Pump
Antroduodenal coordination
Antroduodenal coordination
saline emptying
Slow emptying
Slow emptying
Solid emptying
Solid emptying
Empt. of potato dumpling
Gastric sieving
Gastric sieving
Final emptying
Pump of the reservoir
Viscous meal

Gastric Motor Regulation

Gastric Balance
Normal gastric balance
Effect of gastrin
Effect of gastrin
Effect of insulin
Vagal stimulation
Dopamine control
Dopamine control
A lower dose of dopamine
Gastric Tone
A higher dose of dopamine
Gastric relaxation
What is the alkaline diet: is it true?

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Blood Physiology is great! Let’s discover how interesting it is

I guess you find blood physiology difficult. Even worse it is still in the research stage, so many of the new functions are not found in textbooks. Don’t panic let’s take baby steps to understand it

Blood Buffers

What are blood pH buffers? What is the equation for the buffer system of blood? The isohydric principle. What is the buffer base of the blood? How does the bicarbonate buffer work? How do oxyhemoglobin and deoxyhemoglobin work?

All about hematopoiesis

What is hematopoiesis and how are hematopoietic stem cells regulated in niches?

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All you need to know to understand pH Body Balance

Are you trying to catch the pH Balance? Don´t panic!! It is a complex subject. To fully understand it you must start from the beginning: What is pH? Why it is important? Then go slowly through each aspect until you fully integrate all. So let´s begin the journey….

Why is pH regulation important?

They always tell me about the importance of pH. Why? Here I tell you why pH is so important

Strong and weak acids

In this video, I tell you that it is a strong acid and a weak one. What is a strong or weak base? What does the pKa tell us about the reaction? It is strong or weak?

Effect of pH on enzymes

In this video, I tell you the reason why pH is important in biological systems. Why does enzyme activity change with pH? Is it the same in lipids? Carbohydrates? Nucleic Acids?

The acidic body metabolism

Help! My body is an acid fabric! In this video, I explain why, even though body pH is always around 7.4, body pH is always been challenged by an acidic metabolism.

How do buffers work?

Help! My stomach is burning!!! PLEASE GIVE SOME TUMS! Why do Tums work when our stomach is acidic? In this video, I explain: what are pH Buffers. When a pH Buffer is a good one? Which ph buffer to use? What does it mean when pH equals PKA?

Measuring pH in the lab

In this video, I tell you how to measure pH with a pH meter or pH strips

Blood Buffers

What are blood pH buffers? What is the equation for the buffer system of blood? The isohydric principle. What is the buffer base of the blood? How does the bicarbonate buffer work? How do oxyhemoglobin and deoxyhemoglobin work?

Bicarbonate reabsorption

Learn Step by step how the kidney reabsorbs bicarbonate in the proximal tubule.

Alkaline diet

Alkaline diets are a hot topic but are they healthy? What has been proven? Here I tell you what is an alkaline diet and what it produces in the body. Also, what is the relation between an alkaline diet and some diseases like osteoporosis and cancer?

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